How to take omeprazole, a powerful stomach medicine？ How to stop taking medicine？ The doctor told you in detail

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Omeprazole (PPI), as a first-line drug for the treatment of gastric diseases, is almost an essential medicine for the families of patients with gastric diseases. The price of omeprazole is expensive and cheap, ranging from a few dollars, tens of dollars to hundreds of dollars. However, no matter how its price changes, it can’t change the fact that it has pharmacological effects.

Although omeprazole is a good hand in treating stomach diseases, if we take it incorrectly, it will also bring harm to our health, such as kidney diseases, osteoporosis or fractures.

I met a patient before, because he always had stomach trouble and was very uncomfortable, so he took omeprazole for a long time. Results During a physical examination, he found that creatinine, an indicator of renal function, had increased. Fortunately, the patient’s creatinine dropped to normal after stopping taking the drug.

Omeprazole was used in clinic in 1982, and it still plays an important role in treating peptic ulcer and gastroesophageal reflux disease. Before that, it was generally believed that its side effects were small and not serious, but in recent years, there have always been reports that individual patients will have serious side effects. Although it is rare and uncommon, we can’t completely deny its serious side effects. Therefore, when we take omeprazole, we should consider it comprehensively. It is not a very disease, and we should never take it for a long time.

When should I take omeprazole?

Omeprazole (PPI) is a powerful stomach drug, which can block the activity of H+-K+-ATPase on gastric parietal cells, thus effectively inhibiting the secretion of gastric acid. It is often used to treat gastrointestinal diseases such as peptic ulcer, gastroesophageal reflux and radical eradication of Helicobacter pylori. When we take medicine to treat gastropathy, we must use the medicine based on gastroscopy in the past four months and diagnosis of peptic ulcer, mild and moderate gastroesophageal reflux and other diseases.

In order to kill Helicobacter pylori, the medication time is controlled at 2 weeks.

Patients with peptic ulcer and mild to moderate gastroesophageal reflux should be treated with omeprazole for a maximum of 4 months.

Patients with severe gastroesophageal reflux must be used for one year on the basis of doctor’s advice and regular follow-up.

The pathological diagnosis is Barry’s esophagus, so it is recommended to take medicine for one year, and the condition should be followed up within one year.

Ulcer is always difficult to cure over and over again, and patients who always get sick take medicine for one year.

Patients with perforated peptic ulcer who were cured by gastroduodenal repair were treated with omeprazole for 4 months.

Non-steroidal anti-inflammatory drugs, such as aspirin, need to be used, and omeprazole is needed to treat peptic ulcer. It must be used under the comprehensive evaluation of doctors as early as possible.

Omeprazole used to be a prescription drug, but now it can be purchased in pharmacies. What is a prescription drug? That is, drugs prescribed under the guidance and advice of doctors can bring a lot of help to patients. Omeprazole is from absolute prescription drugs to between prescription drugs and over-the-counter drugs. If you buy it in a pharmacy by yourself, it will bring great side effects to patients because you don’t understand a lot.

An authoritative clinical research report pointed out that 70% of patients who use proton pump inhibitors do not meet the clinical indications.

Therefore, we can take omeprazole only with the guidance and advice of doctors and comprehensive evaluation by doctors. Otherwise, the personal medication time shall not exceed 14 days.

How to eat omeprazole?

For omeprazole, it can’t immediately relieve the symptoms of stomach diseases, and at least after taking the medicine for four days, the full benefits of the medicine can be harvested. Therefore, when we take omeprazole, we must not be impatient, and we should slowly exert its maximum efficacy.

In clinical practice, omeprazole is divided into enteric-coated tablets, capsules and intravenous injection. Regardless of the form of omeprazole, the typical adult dose is generally the following:

For the treatment of gastroesophageal reflux disease, peptic ulcer, erosive esophagitis and helicobacter pylori infection, the daily dose is 20-40 mg.

To prevent upper gastrointestinal bleeding: 40 mg per day.

For the treatment of Zhuo-Ai syndrome, the dosage is different, and it can reach 120mg at most three times a day.

Treat heartburn 20 mg a day.

Take omeprazole at least half an hour to an hour before meals. Be sure to swallow the whole tablet or capsule and take it with water. During this period, don’t chew, crush or split, and don’t take too much or too little.

If taking omeprazole in excess, users may have nausea and vomiting, rapid heartbeat, excessive sweating, dry mouth, and even blurred vision and headache in severe cases. At this time, we should go to the hospital immediately. Since you can’t take too much medicine, some people always forget to take it or miss it when taking it. So what should we do at this time?

Attention, don’t take it for granted. I forgot to take the medicine, so I should take it again. If the interval between taking the next medicine is long, that’s fine. If the interval between taking the next medicine is short, then we must skip the missed dose and operate according to the regular medication schedule, and don’t double the dose to make up for the missed dose.

How to reduce and stop taking omeprazole after taking it for a long time?

In fact, the reduction and withdrawal of omeprazole is the common concern of almost all patients with gastric diseases. It is worth noting that once a patient has received omeprazole medication, he must never feel good about himself and reduce or stop taking it privately. This is a matter of principle. The correct way is to decide whether to reduce or stop taking drugs under the guidance and advice of doctors.

Although taking omeprazole requires a doctor’s advice to stop taking it, I still want to tell you what kind of situation is suitable for reducing or stopping taking it. What should I do after stopping taking the medicine?

For patients who take omeprazole, if there are no obvious symptoms, they can stop taking it. But we should closely follow up whether there are other changes in the condition and whether it recurs. This is a problem that everyone should pay attention to.

If patients with mild or moderate gastroesophageal reflux disease have been treated with omeprazole for 4-8 weeks, and the symptoms have tended to improve or have no symptoms, the dosage can be reduced, and the drug should not be stopped, and once the symptoms appear, they should continue to take medicine. It should be noted that an absolute follow-up mechanism is needed in this process, that is, regular review of gastroscope.

For peptic ulcer that has been treated for 2-12 weeks, the symptoms of upper abdominal discomfort have improved after taking medicine, omeprazole is taken preventively to treat pressure ulcer, or Helicobacter pylori is positive and asymptomatic for 14 days, these situations can be stopped. After stopping the drug, it is still necessary to observe the changes of the disease regularly.

For severe gastroesophageal reflux disease, Barrett’s esophagus diagnosed, peptic ulcer with upper gastrointestinal bleeding, long-term use of non-steroidal anti-inflammatory drugs with high risk of bleeding, these situations need to continue taking drugs, and then we must follow the doctor’s guidance and make regular reduction.

No matter in which case, you must change your eating habits and adjust your diet. For example, eat less greasy food, spicy food, etc. In addition, in life, you should give up drinking, smoking and coffee, especially avoid eating two or three hours before going to bed.

Side effects and precautions of long-term use of omeprazole

As we all know, drugs are toxic in three ways, which means that each drug has its corresponding side effects. Although omeprazole is a relatively safe drug, taking it for a long time can do us great harm.

1. Renal function damage: The renal function damage caused by long-term use of omeprazole is mainly manifested in acute renal damage caused by acute interstitial nephritis. Some severe patients even need temporary dialysis to recover. Fortunately, this usually happens, and most patients can recover their renal function after stopping taking drugs.

Precautions: Although patients with renal dysfunction are rare, there are real reports in the literature. Since this is the case, we have to take some preventive measures during the medication, such as regular examination of renal function, urine routine, blood routine, etc. If there is abnormality, then we should stop taking the medicine decisively.

2, change the pH of the intestine: Omeprazole can inhibit gastric acid secretion, taking it will inevitably make our gastrointestinal pH imbalance. Losing an environment conducive to the growth of intestinal flora will inevitably lead to the imbalance of intestinal flora, which will lead to the growth of certain microorganisms, such as Clostridium difficile, resulting in acute gastroenteritis.

Precautions: check the gastroscope once every six months to see the changes in the stomach. There is some diarrhea, so you should stop taking the medicine. In addition, usually eat more probiotics to balance the intestinal flora.

3. Increased risk of fracture and osteoporosis: Omeprazole will inhibit the secretion of gastric acid, and the secretion of gastric acid will be reduced, which will lead to the increase of osteoclast activity, thus destroying bone and causing osteoporosis or fracture.

The FDA research of the US Food and Drug Administration shows that the use of omeprazole will increase the risk of fracture of hip joint, wrist joint or spine, and it is recommended to use the lowest effective dose or shorten the course of treatment as much as possible.

Precautions: People who are taking omeprazole should pay close attention to the pain in the back, especially the diffuse pain along the spine to both sides of the waist, and the pain can be alleviated by changing the posture. For example, the pain is fine when sitting up, and it will be painful once standing and bending for a long time. This is actually a warning signal of osteoporosis. Once these bad signals appear, you must go to the hospital immediately to ask the doctor’s opinion.

4. Atrophic gastritis: The incidence of this side effect is actually rare. Because it is rare, people always choose to ignore it. Atrophic gastritis is closely related to the occurrence of gastric cancer, so we should take more precautions. In addition, if type A atrophic gastritis, it will also lead to anemia in our body.

Note: Omeprazole’s acid inhibition effect is second only to lansoprazole, but also stronger than esomeprazole, pantoprazole and rabeprazole, so when we take Omeprazole to produce side effects, we can choose some drugs with weak acid inhibition effect. In addition, anemia has occurred, and we should take vitamin B12 together with iron. It is worth noting that we must increase the dosage and time of iron agent when we have not stopped Laszlo drugs.

All the side effects of omeprazole mentioned above are only serious side effects that are harmful to us. In a thousand words, that is to say, when taking omeprazole for a long time, we must regularly check gastroscopy, liver and kidney function, blood routine, urine routine and so on. Omeprazole is indeed a good medicine for treating stomach diseases, but it is precisely because it is a good medicine that we should take it seriously, let it give full play to its efficacy and provide us with "quality service".

Conclusion: Omeprazole is a commonly used drug in clinic. Without it, there will be a "right hand man" in the treatment of stomach diseases. Since it is so important to the clinic, we should make clear the clinical indications of omeprazole, both doctors and patients, and give full play to its positive and positive therapeutic effect on human body.

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Original title: "How to eat omeprazole, a powerful stomach medicine? How to stop taking medicine? The doctor tells you in detail.

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